diff --git a/NEWS b/NEWS
index 3c4d6993f46c..e1ad376f3355 100644
--- a/NEWS
+++ b/NEWS
@@ -21,6 +21,8 @@ PHP                                                                        NEWS
   . Deprecate specifying a nullable return type for __debugInfo(). (timwolla)
   . Fixed bug GH-22142 (Assertion failure in zendi_try_get_long() on IS_UNDEF).
     (David Carlier)
+  . Fixed GH-22060 (Use-after-free when an autoloader unregisters itself
+    during dispatch). (iliaal)
 
 - BCMath:
   . Added NUL-byte validation to BCMath functions. (jorgsowa)
@@ -200,6 +202,8 @@ PHP                                                                        NEWS
 
 - Sqlite3:
   . Fix NUL byte truncation in sqlite3 TEXT column handling. (ndossche)
+  . Fixed GH-22122 (Use-after-free in the authorizer callback when it releases
+    the authorizer). (iliaal)
 
 - Standard:
   . Fixed bug GH-19926 (reset internal pointer earlier while splicing array
diff --git a/Zend/zend_API.h b/Zend/zend_API.h
index 2487c8b632f2..3ad993b278e8 100644
--- a/Zend/zend_API.h
+++ b/Zend/zend_API.h
@@ -860,7 +860,14 @@ static zend_always_inline void zend_call_known_fcc(
 		memcpy(func, fcc->function_handler, sizeof(zend_function));
 		zend_string_addref(func->op_array.function_name);
 	}
+	zend_object *pinned_object = fcc->object;
+	if (pinned_object) {
+		GC_ADDREF(pinned_object);
+	}
 	zend_call_known_function(func, fcc->object, fcc->called_scope, retval_ptr, param_count, params, named_params);
+	if (pinned_object) {
+		OBJ_RELEASE(pinned_object);
+	}
 }
 
 /* Call the provided zend_function instance method on an object. */
diff --git a/ext/pdo_sqlite/tests/gh22122.phpt b/ext/pdo_sqlite/tests/gh22122.phpt
new file mode 100644
index 000000000000..ae15d7490ed2
--- /dev/null
+++ b/ext/pdo_sqlite/tests/gh22122.phpt
@@ -0,0 +1,40 @@
+--TEST--
+GH-22122 (Use-after-free in Pdo\Sqlite authorizer when callback releases the authorizer)
+--EXTENSIONS--
+pdo_sqlite
+--FILE--
+<?php
+$db = Pdo\Sqlite::connect('sqlite::memory:');
+
+class Auth {
+    public string $state = "alive";
+
+    public function authorize(int $action, ...$args): int {
+        global $db;
+        $db->setAuthorizer(null);
+        echo "method: ", $this->state, "\n";
+        return Pdo\Sqlite::OK;
+    }
+}
+$auth = new Auth();
+$db->setAuthorizer([$auth, 'authorize']);
+unset($auth);
+$db->exec('SELECT 1');
+
+$capture = "closure-alive";
+$closure = function (int $action, ...$args) use (&$capture, $db): int {
+    $db->setAuthorizer(null);
+    echo "closure: ", $capture, "\n";
+    return Pdo\Sqlite::OK;
+};
+$db->setAuthorizer($closure);
+unset($closure);
+$db->exec('SELECT 2');
+
+$db->exec('SELECT 3');
+echo "post-disable query ok\n";
+?>
+--EXPECT--
+method: alive
+closure: closure-alive
+post-disable query ok
diff --git a/ext/spl/tests/autoloading/gh22060.phpt b/ext/spl/tests/autoloading/gh22060.phpt
new file mode 100644
index 000000000000..50dff5d71b11
--- /dev/null
+++ b/ext/spl/tests/autoloading/gh22060.phpt
@@ -0,0 +1,27 @@
+--TEST--
+GH-22060 (Class autoloader $this freed via spl_autoload_unregister during dispatch)
+--FILE--
+<?php
+
+class Loader {
+    public string $data = "loader-data";
+
+    public function load(string $class): void {
+        spl_autoload_unregister([$this, 'load']);
+        echo $this->data, "\n";
+    }
+}
+
+$obj = new Loader();
+spl_autoload_register([$obj, 'load']);
+unset($obj);
+
+try {
+    new NonExistentClass42();
+} catch (\Throwable $e) {
+    echo $e::class, ": ", $e->getMessage(), "\n";
+}
+?>
+--EXPECT--
+loader-data
+Error: Class "NonExistentClass42" not found
diff --git a/ext/sqlite3/tests/gh22122.phpt b/ext/sqlite3/tests/gh22122.phpt
new file mode 100644
index 000000000000..1df1c3bc0e28
--- /dev/null
+++ b/ext/sqlite3/tests/gh22122.phpt
@@ -0,0 +1,40 @@
+--TEST--
+GH-22122 (Use-after-free in SQLite3 authorizer when callback releases the authorizer)
+--EXTENSIONS--
+sqlite3
+--FILE--
+<?php
+$db = new SQLite3(':memory:');
+
+class Auth {
+    public string $state = "alive";
+
+    public function authorize(int $action, ...$args): int {
+        global $db;
+        $db->setAuthorizer(null);
+        echo "method: ", $this->state, "\n";
+        return SQLite3::OK;
+    }
+}
+$auth = new Auth();
+$db->setAuthorizer([$auth, 'authorize']);
+unset($auth);
+$db->exec('SELECT 1');
+
+$capture = "closure-alive";
+$closure = function (int $action, ...$args) use (&$capture, $db): int {
+    $db->setAuthorizer(null);
+    echo "closure: ", $capture, "\n";
+    return SQLite3::OK;
+};
+$db->setAuthorizer($closure);
+unset($closure);
+$db->exec('SELECT 2');
+
+$db->exec('SELECT 3');
+echo "post-disable query ok\n";
+?>
+--EXPECT--
+method: alive
+closure: closure-alive
+post-disable query ok