diff --git a/CHANGES.rst b/CHANGES.rst
index e887351..daae4de 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -1,8 +1,8 @@
 0.7.0 (unreleased)
 ==================
 
-- No changes yet
-
+- Added a new ini option, ``doctest_subpackage_requires``, that can be used to skip
+  specific subpackages based on required packages. [#112]
 
 0.6.1 (2020-05-04)
 ==================
diff --git a/README.rst b/README.rst
index 4f624d6..76b52e7 100644
--- a/README.rst
+++ b/README.rst
@@ -225,6 +225,17 @@ conditionally skipped if a dependency is not available.
         >>> import asdf
         >>> asdf.open('file.asdf')
 
+Finally, it is possible to skip collecting doctests in entire subpackages by
+using the ``doctest_subpackage_requires`` in the ``[tool:pytest]`` section of
+the package's ``setup.cfg`` file. The syntax for this option is a list of
+``path = requirements``, e.g.::
+
+    doctest_subpackage_requires =
+        astropy/wcs/* = scipy>2.0;numpy>1.14
+        astropy/cosmology/* = scipy>1.0
+
+Multiple requirements can be specified if separated by semicolons.
+
 Remote Data
 ~~~~~~~~~~~
 
diff --git a/pytest_doctestplus/plugin.py b/pytest_doctestplus/plugin.py
index d3d2870..e6556a2 100644
--- a/pytest_doctestplus/plugin.py
+++ b/pytest_doctestplus/plugin.py
@@ -115,6 +115,12 @@ def pytest_addoption(parser):
                   type='linelist',
                   default=[])
 
+    parser.addini("doctest_subpackage_requires",
+                  "A list of paths to skip if requirements are not satisfied. Each item in the list "
+                  "should have the syntax path=req1;req2",
+                  type='linelist',
+                  default=[])
+
 
 def get_optionflags(parent):
     optionflags_str = parent.config.getini('doctest_optionflags')
@@ -168,12 +174,10 @@ def collect(self):
                 try:
                     module = self.fspath.pyimport()
                 except ImportError:
-                    pytest.skip("unable to import module %r" % self.fspath)
-                    # NOT USED: While correct, this breaks existing behavior.
-                    # if self.config.getvalue("doctest_ignore_import_errors"):
-                    #     pytest.skip("unable to import module %r" % self.fspath)
-                    # else:
-                    #     raise
+                    if self.config.getvalue("doctest_ignore_import_errors"):
+                        pytest.skip("unable to import module %r" % self.fspath)
+                    else:
+                        raise
 
             options = get_optionflags(self) | FIX
 
@@ -410,6 +414,14 @@ def get_list_opt(name):
                 self._ignore_paths.append(path)
                 break
 
+        for option in config.getini("doctest_subpackage_requires"):
+            subpackage_pattern, required = option.split('=', 1)
+            if path.check(fnmatch=subpackage_pattern.strip()):
+                required = required.strip().split(';')
+                if not DocTestFinderPlus.check_required_modules(required):
+                    self._ignore_paths.append(path)
+                    break
+
         return False
 
     def pytest_collect_file(self, path, parent):
diff --git a/pytest_doctestplus/utils.py b/pytest_doctestplus/utils.py
index 236f611..4463cea 100644
--- a/pytest_doctestplus/utils.py
+++ b/pytest_doctestplus/utils.py
@@ -78,7 +78,6 @@ def find_distribution(self, dist):
         try:
             return self._find_distribution(dist)
         except Exception as e:
-            logger.warning(e)
             return None
 
     def check(self, module):
diff --git a/tests/test_doctestplus.py b/tests/test_doctestplus.py
index 249d5f6..5a1e8f7 100644
--- a/tests/test_doctestplus.py
+++ b/tests/test_doctestplus.py
@@ -1,3 +1,4 @@
+import os
 from distutils.version import LooseVersion
 from textwrap import dedent
 
@@ -651,3 +652,41 @@ def test_doctest_float_replacement(tmpdir):
 
     doctest.testfile(str(test2_rst), module_relative=False,
                      raise_on_error=True, verbose=False, encoding='utf-8')
+
+
+def test_doctest_subpackage_requires(testdir, caplog):
+
+    # Note that each entry below has different whitespace around the = to
+    # make sure that all cases work properly.
+
+    testdir.makeini(
+        """
+        [pytest]
+        doctest_subpackage_requires =
+            test/a/* = pytest>1
+            test/b/*= pytest>1;averyfakepackage>99999.9
+            test/c/*=anotherfakepackage>=22000.1.2
+    """
+    )
+    test = testdir.mkdir('test')
+    a = test.mkdir('a')
+    b = test.mkdir('b')
+    c = test.mkdir('c')
+
+    pyfile = dedent("""
+        def f():
+            '''
+            >>> 1
+            1
+            '''
+            pass
+    """)
+
+    a.join('testcode.py').write(pyfile)
+    b.join('testcode.py').write(pyfile)
+    c.join('testcode.py').write(pyfile)
+
+    reprec = testdir.inline_run(test, "--doctest-plus")
+    reprec.assertoutcome(passed=1)
+    assert reprec.listoutcomes()[0][0].location[0] == os.path.join('test', 'a', 'testcode.py')
+    assert caplog.text == ''